“I think there are many actresses that could play it because there are so many wonderful actresses,” said Smith. “I mean, it would change the role because she would be a woman so when you put her in a room full of men, it’s a different scenario than if you put a man in a room full of men, because she’s a different sex.
“Would it change the fundamentals of the character? No. But it’s an interesting idea. If the Doctor’s a woman, does she have a Doctor baby? Is there a mini-Doctor? I don’t know, who knows?”
He added that it’s unlikely to happen, although he’d love to see Prometheus‘ Charlize Theron in the role, saying, “Oh gosh, so many, so many could play her. It depends on what age you would want,” he mused “It could be… Charlize Theron is pretty kick-ass, isn’t she?
“They just have to find a brilliant actress. I never see that happening any time soon, to be honest.”
Doctor Who Series 7 is currently showing on BBC One HD and BBC America.